DUAL-TARGETING OF HPV-DRIVEN CANCERS
Our research is focused on establishing a novel dual-targeting therapeutic strategy, that targets both the unique E6 and E7 -dependent features and the general stress protection machinery to eliminate Human papillomavirus-driven cancers. Based on our previous findings our researchers are developing a small molecule-based combination therapy that specifically eliminates the cancer-promoting mechanisms. The main goal of the research is to find new therapeutic measures to specifically eliminate tumors caused by HPV infection.
“In our recent studies, our research team has found a completely new way to eliminate HPV-infected cells and thus prevent the development of cancers caused by HPV.
— John Eriksson
“Our research group has found a mechanism that significantly reduces the stress tolerance of cancer cells and thus their viability, based on the cellular defense mechanisms that are responsible for regulating gene expression in stressful conditions.
— Lea Sistonen